Discussion
The pair of amino-acids which does NOT undergo post-translational modification is
Answer: D
The pair that does not undergo post-translational modification is Ala-Gly.
Post-translational modifications act on reactive side chains, and alanine (a methyl group) and glycine (a hydrogen atom) have none to modify. (An N-terminal glycine can be myristoylated, but that acts on the chain's terminal amino group, not on a side chain.)
Every other pair includes a commonly modified residue. Asparagine is the site of N-linked glycosylation. Serine and tyrosine are phosphorylated by kinases, and serine also carries O-linked sugars. Histidine can be phosphorylated (as in bacterial two-component signalling) and methylated.
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