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Which one of the following statements about gene expression is INCORRECT?

  • A.DNA is transcribed to mRNA.
  • B.mRNA can be reverse-transcribed to DNA.
  • C.mRNA can be translated to protein.
  • D.Protein can be reverse-translated to mRNA.

Answer: D

The incorrect statement is Protein can be reverse-translated to mRNA.

The central dogma allows information to pass from DNA to RNA (transcription), from RNA back to DNA (reverse transcription, by retroviral reverse transcriptase) and from mRNA to protein (translation). It does not allow transfer from protein back to nucleic acid: no enzyme reads an amino acid sequence to build mRNA, and the degeneracy of the code would leave the sequence undetermined anyway.

The other three statements describe processes that do occur.

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