Discussion
Codon bias is correlated with the relative frequencies of which one of the following types of RNA?
Answer: D
Codon bias correlates with the relative abundance of tRNA.
Synonymous codons for the same amino acid are not used equally. In highly expressed genes the preferred codons are those read by the most abundant tRNA species in the cell, which speeds and improves the accuracy of translation. Codon usage tables and tRNA gene copy numbers track each other across organisms.
mRNA carries the codons but its abundance does not explain which synonym is preferred. rRNA forms the ribosome and is the same for every codon, and siRNA acts in gene silencing, not in decoding.
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