Discussion
The E-factor exposes a problem that atom economy misses, namely the
Answer: A
Correct answer: mass of solvent and auxiliaries used
Atom economy is computed from the balanced equation and therefore sees only the reagents that appear in it. Solvent, water, drying agents and chromatography media appear nowhere in the equation and yet are usually the largest part of the mass consumed. The E-factor counts everything that leaves as waste, which is why the two figures can point in opposite directions.
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