Discussion
Avoiding a protecting group in a synthesis is desirable because each protection step
Answer: B
Correct answer: adds reagents, steps and waste without building the product
A protecting group must be put on and taken off again, so it contributes two steps, two sets of reagents and two lots of waste, and the molecule ends up exactly where it would have been without it. Designing a route that needs none, often by using a more selective catalyst or enzyme, removes that whole burden.
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