Discussion
IgM antibody to the hepatitis B core antigen indicates
Answer: D
Correct answer: recent or acute infection
IgM is the first class of antibody made and it wanes over a few months, so IgM anti-HBc points to infection within roughly the last six months. IgG anti-HBc persists for life and shows only that infection occurred at some time, which is why the two classes must be distinguished.
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