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Discussion

Hepatitis B e antigen in serum indicates

  • A.active viral replication and high infectivity
  • B.successful clearance of the virus
  • C.immunity conferred by the vaccine
  • D.past infection with no current virus

Answer: A

The e antigen is produced during vigorous replication, so its presence marks a highly infectious phase, which matters greatly in pregnancy and after a needlestick. Its loss and the appearance of anti-HBe usually mark a fall in replication.

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