Discussion
Testing a vaccinated person for hepatitis B immunity means measuring
Answer: A
Correct answer: antibody to the surface antigen
The vaccine contains only the surface antigen, so a response to it is measured as anti-HBs. A level of 10 international units per litre or more is taken as protective. Anti-HBc would be absent in someone vaccinated but never infected, and the surface antigen itself would indicate infection rather than immunity.
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