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Down's syndrome is associated with :

  • A.Trisomy 21
  • B.Cri du chat syndrome
  • C.XXY chromosome combination
  • D.XO chromosome aberration

Answer: A

Down's syndrome is associated with trisomy 21.

Most people with Down's syndrome have three copies of chromosome 21 instead of two, usually because the chromosomes failed to separate when the egg or sperm formed. It causes intellectual disability and characteristic physical features, and its risk rises with maternal age.

Cri du chat syndrome is caused by a deletion on chromosome 5. The XXY combination is Klinefelter syndrome, and the XO pattern (a single X chromosome) is Turner syndrome.

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