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The Genain quadruplets are known because :

  • A.all became artists
  • B.all developed schizophrenia
  • C.all were conceived with IVF
  • D.all died early

Answer: B

The Genain quadruplets are known because all developed schizophrenia.

The Genain sisters were identical quadruplets born in the United States in 1930, and all four were diagnosed with schizophrenia. David Rosenthal and colleagues at the National Institute of Mental Health studied them in detail (1963), and the case is a standard illustration of a genetic contribution to schizophrenia. The sisters differed in severity and outcome, which also showed the role of environment.

They are not known for becoming artists, were conceived naturally decades before IVF existed, and did not all die early; several lived into old age.

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