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Discussion

Match List-I with List-II and select the correct answer using the codes given below :

List I (Name of disorder or Syndrome)List II (Description)
(P) Asperger's disorder(1) Genetic condition affecting males causing cognitive impairment
(Q) Down's syndrome(2) Trisomy 21 causing MR
(R) Fragile X syndrome(3) Chromosomal condition affecting females
(S) Turner's syndrome(4) Difficulty in social interaction

  • A.P-3, Q-1, R-2, S-4
  • B.P-2, Q-3, R-4, S-1
  • C.P-4, Q-2, R-1, S-3
  • D.P-1, Q-4, R-3, S-2

Answer: C

The correct matching is P-4, Q-2, R-1, S-3.

  • P: Asperger's disorder is marked by difficulty in social interaction without significant delay in language or cognitive development (4).
  • Q: Down's syndrome is caused by trisomy 21, an extra chromosome 21, and causes intellectual disability (MR) (2).
  • R: Fragile X syndrome is an X-linked genetic condition that affects males more often and more severely, causing cognitive impairment; it is the most common inherited cause of intellectual disability (1).
  • S: Turner's syndrome (45,X) is a chromosomal condition affecting females who have a single X chromosome (3).

The other codes give the trisomy, the X-linked condition or the female chromosomal condition to the wrong syndrome.

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