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Pseudohermaphroditism is a condition in which the individual is insensitive to ....................

  • A.Androgen
  • B.Estrogen
  • C.Progesterone
  • D.Corticosterone

Answer: A

The insensitivity is to androgen.

In male pseudohermaphroditism due to androgen insensitivity syndrome, a 46,XY individual has testes that make testosterone normally, but the androgen receptor does not respond to it. External genitalia develop along female lines and, in the complete form, the person appears female, though without a uterus.

Insensitivity to oestrogen, progesterone or corticosterone does not change the development of the genitalia in this way, since male differentiation depends on androgen action.

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