Discussion

Match the syndromes listed in Column I with the cause/symptoms listed in Column II

Column I	Column II
P. Prader-Willi syndrome	(i) a collection of signs and symptoms due to prolonged exposure to corticosteroids like cortisol
Q. Down syndrome	(ii) a syndrome of inadequate reabsorption in the proximal renal tubule of the kidney
R. Cushing syndrome	(iii) a genetic disorder usually caused by the deletion of a part of chromosome 15
S. Turner syndrome	(iv) a genetic disorder caused by the presence of all or part of a third copy of chromosome 21
T. Fanconi syndrome	(v) a genetic condition in which a female has partially or completely missing an X chromosome

Answer: C

The match is P-(iii); Q-(iv); R-(i); S-(v); T-(ii).

Prader-Willi syndrome is usually caused by loss of the paternal copy of a region of chromosome 15 (15q11-q13).
Down syndrome is caused by a third copy of all or part of chromosome 21.
Cushing syndrome results from prolonged exposure to high levels of corticosteroids such as cortisol.
Turner syndrome is a female with one X chromosome partly or wholly missing (45,X).
Fanconi syndrome is a failure of reabsorption in the proximal renal tubule.

The other options swap the chromosomal disorders or attach the kidney or steroid descriptions to genetic syndromes.

No comment is present. Be the first to comment.

Loading…