Discussion
Haemophilia disease is more commonly seen in males because
Answer: A
Haemophilia is commoner in males because it is an X-linked disease.
The genes for clotting factors VIII and IX lie on the X chromosome, and haemophilia is X-linked recessive. A male has only one X chromosome, so a single defective copy causes the disease. A female has two X chromosomes and is usually only a carrier unless both are affected, which is rare.
An autosomal disease would affect both sexes equally. A Y-linked trait would pass only from father to son, which is not haemophilia's pattern. It is a blood clotting disorder, not a disease of the reproductive system.
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