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Discussion

The maturation of T cells and the production of particular T cell receptors occurs in the

  • A.thyroid gland
  • B.thymus gland
  • C.testes
  • D.
    all of these

Answer: B

Correct answer: thymus gland

T cells are made in the bone marrow but mature in the thymus - which is what the T stands for. There they rearrange their receptor genes and are then screened twice: cells whose receptor cannot recognise self MHC die, and cells that react too strongly to the body’s own antigens are deleted. Only about 2% survive both tests.

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