Discussion
Inflammatory response in allergy is due to release by mast cells of
Answer: C
Correct answer: Histamine
Histamine is the principal mediator released when allergen cross-links IgE bound to a mast cell. It dilates small vessels, makes them leaky and contracts smooth muscle - producing the itching, swelling, runny nose and bronchoconstriction of an allergic reaction, which is why antihistamines relieve them.
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