Discussion
What is the commonest reversed phase packing?
Answer: C
Octadecylsilane, universally written as C18, is bonded to silica particles and provides the non-polar surface. Bare silica is the normal phase packing, alumina is little used now, and polymer beads serve ion exchange and size exclusion. That one packing chemistry accounts for the large majority of all separations makes it the sensible starting point for any method development.
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