Discussion
What does an evaporative light scattering detector respond to?
Answer: B
The eluent is nebulised and evaporated, leaving particles of anything less volatile, which scatter a light beam in proportion to their amount. Absorbance, fluorescence and charge are the bases of other detectors. Near-universality for involatile analytes, and compatibility with gradients, is what recommends it - at the cost of a response that is not linear and depends on particle size. The shared properties explain why these belong to one family, and the differences explain why more than one exists.
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