Discussion
What is a monolithic column?
Answer: D
A monolith is one continuous piece of porous silica or polymer with large flow-through channels and fine pores for retention, so the eluent passes readily while the surface area stays high. It contains no particles, no second phase and is not defined by its casing. Separating the flow path from the retentive surface is what lets a monolith run at high flow with modest pressure.
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