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What is the drawback of electron impact for a fragile molecule?

  • A.The molecular ion may not survive
  • B.The fragments are too small to interpret
  • C.The technique requires a solution rather than a vapour
  • D.The ionisation efficiency is too low to detect

Answer: A

With so much excess energy a labile molecule fragments completely and no molecular ion appears, so the molecular weight cannot be read from the spectrum. The fragments are informative rather than uninterpretable, the sample must be a vapour, and efficiency is good. Losing the one peak that gives the molecular weight is what drove the development of the softer ionisation methods.

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