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What pressure does a mass spectrometer typically operate at?

  • A.About one millibar
  • B.Slightly below atmospheric pressure
  • C.About a millionth of a millibar
  • D.About a thousandth of a millibar

Answer: C

The analyser runs at around ten to the minus six millibar, where the mean free path is tens of metres and collisions are rare. A thousandth of a millibar is roughly the source pressure in chemical ionisation, and the higher figures would scatter every ion. Two or three pumping stages in series are needed to reach it from atmosphere, which is much of the instrument's bulk and cost.

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