Discussion
Why the bacterium Treponema pallidum is difficult to culture?
Answer: C
Correct answer: Because it lacks the genes needed for TCA cycle and oxidative phosphorylation
The genome of Treponema pallidum shows it cannot make its own amino acids, nucleotides or fatty acids, and lacks a complete respiratory chain, so it depends on the host for compounds no ordinary medium supplies. The sequence explained a difficulty that had defeated bacteriologists for a century.
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