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Which of the following organisms has the smallest genome?

  • A.H. influenzae
  • B.M. genitalium
  • C.M. tuberculosis
  • D.None of these

Answer: B

Correct answer: M. genitalium

Mycoplasma genitalium has about 580,000 base pairs and some 470 genes, among the smallest of any cell able to replicate independently. Its economy comes from parasitism - it takes most of what it needs from its host - which is why it has been used to investigate the minimum gene set for life.

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