Discussion
Which of the following statements is correct?
Answer: A
Correct answer: Phosphate repression can not be eliminated by optimization of nutrient medium, deregulated medium must be used as production strains
Phosphate represses the enzymes of many secondary metabolic pathways, and the repression cannot simply be lifted by adjusting the medium - phosphate is also needed for growth, so there is no concentration that both feeds the culture and releases the pathway. Industry therefore uses phosphate-deregulated mutants, strains selected to be insensitive to the repression.
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