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Dolichol phosphate is

  • A.a complex lipid involved in docking vesicles with the plasma membrane
  • B.the anchor on which sugars assemble before transfer to proteins
  • C.a chaperone used in protein folding
  • D.a product of phospholipase C activation

Answer: B

Correct answer: the anchor on which sugars assemble before transfer to proteins

Dolichol phosphate is a long polyisoprenoid lipid embedded in the ER membrane. The core oligosaccharide of an N-linked glycoprotein is built up on it, sugar by sugar, and then transferred as a block to an asparagine residue of the growing protein.

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