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Which of the following nucleoside diphosphates is used most often in carbohydrate anabolism?

  • A.Uridine diphosphate
  • B.Adenosine diphosphate
  • C.Guanosine diphosphate
  • D.Thymidine diphosphate

Answer: A

Correct answer: Uridine diphosphate

UDP is the usual carrier in carbohydrate biosynthesis: sugars are activated as UDP-glucose, UDP-galactose and the like before being transferred to a growing chain. Activation is necessary because the transfer itself is thermodynamically unfavourable, and the UDP leaving group is what pays for it.

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