Discussion
If radioactive bicarbonate was supplied to bacterial cells, which were actively synthesizing fatty acids, it is expected to find the bulk of the radioactivity in
Answer: A
Correct answer: cellular bicarbonate
The CO2 fixed by acetyl-CoA carboxylase to make malonyl-CoA is released again at each condensation step of fatty acid synthesis. So the labelled carbon passes through the pathway and returns to the cellular bicarbonate pool rather than being built into the fatty acid chain, which is assembled entirely from acetyl units.
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