Discussion
In bacterial glucose phosphotransferase system, glucose is converted to glucose 6-phosphate. What is the source of phosphate ?
Answer: C
The phosphate comes from phosphoenol pyruvate (PEP).
In the bacterial phosphotransferase system (PTS), the phosphoryl group of PEP is passed along a relay of proteins: enzyme I, then HPr, then the sugar-specific enzyme II complex. Enzyme II phosphorylates glucose as it carries it across the membrane, so glucose enters the cell already as glucose 6-phosphate. This is group translocation, and PEP becomes pyruvate.
ATP is not the direct donor in the PTS, inorganic phosphate is not used, and creatine phosphate is an energy store of vertebrate muscle, not a bacterial metabolite.
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