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The plasmid which makes the host more pathogenic is

  • A.F factors
  • B.Metabolic plasmid
  • C.Virulence plasmid
  • D.None of these

Answer: C

Correct answer: Virulence plasmid

A virulence plasmid carries genes that make its host more pathogenic - adhesins, invasion determinants, toxins or iron-scavenging systems. The Ent plasmids encoding enterotoxins in Escherichia coli, the pXO1 and pXO2 plasmids of Bacillus anthracis and the invasion plasmids of Shigella are all examples.

An F factor is a fertility plasmid concerned with conjugation and confers no virulence, while a metabolic plasmid encodes degradative or biosynthetic enzymes that widen the range of substrates the cell can use. The classification is by the function the accessory genes serve.

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