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Which type of plasmid can exist with or without being integrated into the host's chromosome?

  • A.Medisome 
  • B.Lisosome
  • C.Lysogen
  • D.Episome

Answer: D

Correct answer: Episome

An episome is a plasmid that can either replicate autonomously in the cytoplasm or integrate into the host chromosome and be replicated as part of it. The F factor of Escherichia coli is the classic example: free in an F+ cell, integrated in an Hfr cell.

A lysogen is a bacterium carrying a prophage, which is a state of the cell rather than a type of plasmid. "Medisome" is not a term in use, and a lysosome is a eukaryotic organelle unrelated to bacterial genetics.

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