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Human mitochondrial DNA is about 16,500 base pairs and encodes 13 proteins. Roughly how many base pairs per encoded protein is that?

  • A.about 127
  • B.about 12,700
  • C.about 165
  • D.about 1,270

Answer: D

Dividing 16,500 by 13 gives about 1,270. The genome also encodes transfer and ribosomal RNAs, so the figure overstates how much is devoted to protein coding alone. It is one of the most compact genomes known, with almost no spare sequence.

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