Discussion
What does an INEPT sequence achieve?
Answer: B
INEPT moves the larger proton polarisation onto carbon or nitrogen, enhancing the weak nucleus by roughly the ratio of the gyromagnetic ratios and allowing repetition at the faster proton relaxation rate. It is the building block behind DEPT, HSQC and much of modern heteronuclear NMR. Solvent suppression, selective inversion and phase correction are each achieved by other means. Polarisation transfer, together with inverse detection, is why nitrogen-15 work at natural abundance became feasible at all.
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