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State whether the following is true or false.
Heterochromatin is generally transcriptionally active.

  • A.True
  • B.False
  • C.True only at large scales
  • D.False only at small scales

Answer: B

Its dense packing excludes the transcription machinery, so it is largely silent. Regions near centromeres and telomeres are permanently heterochromatic, while other regions switch state as the cell changes what it expresses. Facultative heterochromatin is the term for regions that can switch.

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