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State whether the following is true or false.
Epigenetic marks such as DNA methylation change the underlying DNA sequence.

  • A.True
  • B.False
  • C.True only at large scales
  • D.False only at small scales

Answer: B

They alter how a sequence is read without changing a single base, which is precisely what the word epigenetic means. This is why such marks can be reversed while a mutation cannot. That reversibility is what makes epigenetic marks attractive as drug targets.

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