Discussion
Test used for the assessment of thiamin status is :
Answer: D
Thiamin status is assessed by the erythrocyte transketolase activity test.
Transketolase, an enzyme of the pentose phosphate pathway in red cells, needs thiamin pyrophosphate as its coenzyme. The test measures its activity with and without added TPP; a large increase on adding TPP (the TPP effect) shows thiamin deficiency.
The erythrocyte glutathione reductase test assesses riboflavin status, the FIGLU (formiminoglutamic acid) excretion test assesses folate, and the relative dose response test assesses vitamin A stores in the liver.
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