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Give the sequential order of the symptoms of vitamin A deficiency.

I. Night Blindness
II. Keratinization
III. Xerophthalmia
IV. Keratomalacia
Codes :

  • A.I, III, II, IV
  • B.I, II, IV, III
  • C.I, II, III, IV
  • D.II, III, IV, I

Answer: A

The key gives the order of symptoms of vitamin A deficiency as night blindness (I), xerophthalmia (III), keratinization (II) and keratomalacia (IV). Night blindness is the earliest symptom, since the rod pigment rhodopsin is affected first.

The eye then becomes dry and the conjunctiva thickens, the cornea is affected, and the final and most serious stage is keratomalacia, which can lead to blindness. The other codes begin with a later stage or place keratomalacia before the earlier ones.

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