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Which of the following best represents the chemical name of Penicillin V, commonly used as an oral penicillin ?

  • A.Phenoxymethylpenicillin
  • B.Benzathine penicillin
  • C.Procaine penicillin
  • D.Benzylpenicillin sodium

Answer: A

Penicillin V is phenoxymethylpenicillin.

The phenoxymethyl side chain makes it stable in gastric acid, which is why penicillin V is the penicillin given by mouth.

The other three are forms of penicillin G (benzylpenicillin), which acid destroys and which is therefore injected. Benzylpenicillin sodium is the soluble salt for intravenous or intramuscular use. Benzathine penicillin and procaine penicillin are poorly soluble depot salts given intramuscularly so that penicillin G is released slowly over days (benzathine) or about a day (procaine).

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