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Vincristine and Vinblastine are the chemical constituents of :

  • A.Ephedra
  • B.Ginseng
  • C.Vinca
  • D.Rhubarb

Answer: C

Vincristine and vinblastine come from Vinca.

They are alkaloids of the Madagascar periwinkle, Vinca rosea (now Catharanthus roseus). Both bind tubulin and stop the mitotic spindle forming, which halts cell division, so they are used as anticancer drugs: vincristine in leukaemias and lymphomas, vinblastine in Hodgkin's disease and testicular cancer.

Ephedra is the source of ephedrine, ginseng contains ginsenosides, and rhubarb contains anthraquinone purgatives. None of them yields the vinca alkaloids.

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