Discussion
Which of the following membrane associated process involves the step of Clathrin coated vesicle formation during its mechanism ?
Answer: C
Clathrin-coated vesicles form in receptor mediated endocytosis.
Ligands such as LDL bind specific receptors that cluster in clathrin-coated pits on the plasma membrane. Clathrin assembles into a basket-like lattice on the inner face, the pit invaginates, dynamin pinches it off, and a clathrin-coated vesicle carries the cargo inward before the coat is shed.
Phagocytosis engulfs large particles by actin-driven pseudopodia, not by clathrin coats. Amino acid uptake and calcium uptake occur through transporters and channels in the membrane, with no vesicle formation at all.
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