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Integral membrane proteins differ from peripheral ones in that integral proteins

  • A.are embedded within the lipid bilayer
  • B.lie loosely on the membrane surface
  • C.are always found on the outer face only
  • D.consist entirely of carbohydrate chains

Answer: A

Spanning or penetrating the bilayer requires a hydrophobic region that matches the membrane core, and removing such a protein needs a detergent. Peripheral proteins can be washed off by a change of salt concentration alone.

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