Discussion
In every cycle of its activity, at the expense of one ATP molecule, one Na-K ATPase :
Answer: B
One Na-K ATPase extrudes 3 Na+ and takes in 2 K+ per ATP.
In each cycle the pump binds three Na+ on the cytoplasmic side, is phosphorylated by ATP, changes shape and releases them outside; it then binds two K+ from outside, is dephosphorylated and releases them inside.
Moving three positive charges out for every two brought in makes the pump electrogenic, contributing to the negative resting potential. The other options give the wrong numbers (1 : 3 and 1 : 1) or the wrong direction, with K+ going out and Na+ coming in.
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