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Discussion

A Ramchandran plot describes, for a particular amino acid in a polypeptide chain, stearically allowed angles for :

  • A.Cα-C and Cα-CB bonds
  • B.Cα-C and Cα-N bonds
  • C.Cα-C and Cα-H bonds
  • D.Cα-N and Cα-H bonds

Answer: B

The plot describes the allowed angles for the Cα-C and Cα-N bonds.

The Ramachandran plot maps the two backbone torsion angles of each residue: phi (rotation about the N-Cα bond) and psi (rotation about the Cα-C bond). The peptide bond itself is planar, so these two rotations fix the backbone conformation, and the plot shows which combinations avoid steric clashes, the regions of alpha-helix and beta-sheet.

The Cα-CB bond leads into the side chain, and Cα-H bonds carry a hydrogen; rotations about neither are plotted, so every option naming them is wrong.

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