Discussion
The author is most probably leading up to a discussion of some suggestions about how to:
Answer: C
Correct answer: coordinate better the sharing of information among the drug agencies of various nations
The passage builds towards the gap that remains after approval: effects too rare for the trials to catch. Since no single country's trials can find them, the natural next step is pooling what different countries observe after marketing. Improving the trials themselves is the option the passage has just explained cannot solve the problem.
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