Discussion
Catabolite repression in bacteria is regulated by the concentration of
Answer: B
Catabolite repression is regulated by the concentration of glucose.
When glucose is plentiful, bacteria such as E. coli use it first and repress the genes for using other sugars. In E. coli, glucose transport through the phosphotransferase system lowers adenylate cyclase activity, so cAMP falls; without cAMP the CRP (CAP) activator cannot bind its sites, and operons such as lac are transcribed poorly. Glucose uptake also causes inducer exclusion.
Lactose is the inducer of the lac operon, not the regulator of catabolite repression. Amino acid levels regulate attenuation and the stringent response, and mRNA concentration is an outcome of regulation, not its signal.
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