Discussion
Which of the following is the complications of autoimmune reaction from pharyngitis?
Answer: A
Correct answer: Rheumatic fever
Rheumatic fever is the autoimmune sequel to streptococcal pharyngitis: antibody raised against the M protein and the cell wall carbohydrate cross-reacts with myocardium and cardiac valves, producing carditis, arthritis and chorea weeks after the throat infection has settled. Scarlet fever is a toxin-mediated feature of the acute illness, not an autoimmune complication.
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