Discussion
Which of the following is NOT the virulent factor, an important antigenic property of S. pyogenes?
Answer: A
Correct answer: Endotoxins
Endotoxin is lipopolysaccharide, a component of the gram-negative outer membrane, and S. pyogenes is gram-positive and has none. Its virulence rests on the M protein, which resists phagocytosis and is the principal antigen; the streptolysins, which lyse cells; and enzymes such as streptokinase and hyaluronidase, which spread the infection through tissue.
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