Discussion
Which of the following is a major virulence factor of Streptococcus pneumoniae?
Answer: A
Correct answer: polysaccharide capsule
The pneumococcal capsule prevents phagocytosis and is the organism’s principal virulence factor: unencapsulated strains are avirulent. It is also the basis of prevention, since both the polysaccharide and the conjugate vaccines are directed against it, and of typing, there being more than ninety capsular serotypes. M protein and the streptolysins belong to S. pyogenes.
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