Discussion
Which modified amino acid begins most prokaryotic proteins?
Answer: B
Correct answer: N-formylmethionine
Bacterial protein synthesis begins with N-formylmethionine: methionine whose amino group carries a formyl group, delivered by a special initiator tRNA. The formyl group is usually removed afterwards, and often the methionine with it. Our immune system recognises formylated peptides as a signature of bacteria, which is why they are potent chemoattractants for neutrophils.
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