Discussion
Which of the following molecules catalyses the transpeptidation reaction?
Answer: B
Correct answer: Peptidyl transferase
Peptidyl transferase forms the peptide bond, transferring the growing chain from the tRNA in the P site to the amino acid in the A site. It is part of the large subunit - and remarkably, the catalytic activity resides in the rRNA, not in the ribosomal proteins, so the ribosome is a ribozyme.
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