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The DNA coding for the production of cholera toxin in Vibrio cholerae is on the

  • A.phage
  • B.plasmid
  • C.chromosome
  • D.transposon

Answer: C

Correct answer: chromosome

The ctxAB genes are carried by the filamentous bacteriophage CTX, which lysogenises the organism and integrates into the bacterial chromosome, so the genes sit on the chromosome as part of an integrated prophage. That is why a non-toxigenic strain can be converted to a toxigenic one, and why the toxin genes are inherited stably once acquired.

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